Structure and assembly of doublestranded RNA mycoviruses Adv Virus Res ; doi /bsaivir1 Epub Sep 16 Authors Carlos P Mata 1 , Javier M Rodríguez 2 , Nobuhiro Suzuki 3 , José R Castón 4 Affiliations 1 Department of Structure ofStructural basis of tolllike receptor 3 signaling with doublestranded RNA Tolllike receptor 3 (TLR3) recognizes doublestranded RNA (dsRNA), a molecular signature of most viruses, and triggers inflammatory responses that prevent viral spread TLR3 ectodomains (ECDs) dimerize on oligonucleotides of at least 40 to 50 base pairs in length, the minimal length required for siSelect one O RNA strands cannot form base pairs Double stranded DNA is a more stable structure O DNA cannot exist in the single stranded form it is easier to replicate double stranded DNA than single stranded RNA
Fig 1 Structural Basis Of Toll Like Receptor 3 Signaling With Double Stranded Rna Science
